Which agent is an IL-1 receptor antagonist?

Unlock all questions

This demo includes only 20 questions. Upgrade to access hundreds of questions, flashcards, exam simulations, and disable ads.

Full question bankExam simulationsFlashcards
From $9.99Unlock all

Prepare for the CMS II Rheumatology E1 Exam with interactive flashcards and multiple choice questions, each equipped with hints and explanations. Ace your exam today!

Multiple Choice

Which agent is an IL-1 receptor antagonist?

Explanation:
Blocking IL-1 signaling is the key idea. Anakinra is a recombinant IL-1 receptor antagonist that binds to the IL-1 receptor, preventing IL-1 alpha and IL-1 beta from signaling and thus reducing inflammation. This distinguishes it from the others: Tocilizumab blocks the IL-6 receptor, Rituximab depletes CD20+ B cells, and Abatacept interferes with T cell activation by inhibiting CD28 costimulation. Therefore, the agent that acts as an IL-1 receptor antagonist is Anakinra.

Blocking IL-1 signaling is the key idea. Anakinra is a recombinant IL-1 receptor antagonist that binds to the IL-1 receptor, preventing IL-1 alpha and IL-1 beta from signaling and thus reducing inflammation. This distinguishes it from the others: Tocilizumab blocks the IL-6 receptor, Rituximab depletes CD20+ B cells, and Abatacept interferes with T cell activation by inhibiting CD28 costimulation. Therefore, the agent that acts as an IL-1 receptor antagonist is Anakinra.

More Multiple Choice Questions
Subscribe

Get the latest from Examzify

You can unsubscribe at any time. Read our privacy policy